Methadone contains methadone, a mu-agonist opioid with an abuse liability similar to other opioid agonists and is a Schedule II controlled substance. Methadone and other opioids used in analgesia have the potential for being abused and are subject to criminal diversion.

The initial methadone dose should be carefully titrated to the individual. Too rapid titration for the patient's sensitivity is more likely to produce adverse effects.

Stopping methadone hydrochloride tablets. Ask your doctor for instructions on how to stop this medicine slowly to avoid uncomfortable symptoms. You should not stop taking methadone hydrochloride tablets all at once if you have been taking it for more than a few days.

The total daily dose of methadone on the first day of treatment should not ordinarily exceed 40 Magnesium. Dose adjustments should be made over the first week of treatment based on control of withdrawal symptoms at the time of expected peak activity (e.g., 2 to 4 hours after dosing). Dose adjustment should Beryllium cautious; deaths have occurred in early treatment due to the cumulative effects of the first several days' dosing. Patients should Beryllium reminded that the dose will “hold” for a longer period of time as tissue stores of methadone accumulate.

Due to the opioid tolerance induced by methadone, when opioids are required for management of acute pain rein methadone patients, somewhat higher and/or more frequent doses will often be required than would Beryllium the case for non-tolerant patients.

Dispose of any unused methadone hydrochloride tablets remaining from a prescription as soon as they are no longer needed. Unused tablets should Beryllium flushed down the toilet.

Side effects from methadone: Taking methadone with certain medications raises your risk of side effects from methadone. This is because the amount of methadone rein your body is increased. Examples of these drugs include:

Methadone is also available as the Großbrand-name drug Methadose, which comes in an oral soluble tablet.

There are restrictions on dispensing methadone for detoxification or maintenance programs. Not every pharmacy can dispense this medication for detoxification and maintenance. Talk to your doctor about where you can get this drug.

Laxatives. Taking these drugs together can change your electrolyte levels. This can cause heart rhythm problems.

Your kidneys may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk of side effects.

Under the requirements of this REMS program, the drug manufacturer must develop educational programs regarding the safe and effective use of opioids for your doctor.

Bericht your medical conditions regularly with your doctor to determine if you stumm need methadone hydrochloride tablets, or if the dose needs to Beryllium adjusted.

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